cAMP-dependent Protein Kinase
نویسندگان
چکیده
منابع مشابه
THE EFFECT OF THEOPHYLLINE ON THE KINETICS OF cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, cAMP, PROTEIN KINASE INHIBITOR AND THEIR RELATIONSHIP IN LUNG TISSUE
We have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. The results show that the point of highest concentration of the C subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 Ilg/ InL and 10µg/mL theophylline, this is shifted to I.S an...
متن کاملthe effect of theophylline on the kinetics of camp-dependent protein kinase catalytic subunit, camp, protein kinase inhibitor and their relationship in lung tissue
we have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. the results show that the point of highest concentration of the c subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 ilg/ inl and 10µg/ml theophylline, this is shifted to i.s and 2....
متن کاملcAMP-dependent protein kinase activation lowers hepatocyte cAMP.
Rat hepatocyte protein kinase was activated by incubating the cells with various cAMP analogs. Boiled extracts were then prepared and Sephadex G-25 chromatography was carried out. The G-25 procedure separated the analogs from cAMP since the resin had the unexpected property of binding cyclic nucleotides with differing affinities. Separation was necessary because the analogs would otherwise inte...
متن کاملDynamics of cAMP-dependent protein kinase.
B. N-Terminus/C-Terminus 2253 1. N-Terminal Tail 2253 2. C-Terminal Tail 2257 C. Signal Integration Motifs 2257 1. C Helix 2258 2. Activation Loop 2258 3. F Helix 2258 D. Dynamics 2259 1. Fluorescence Anisotropy 2259 2. Molecular Dynamic Simulations 2260 III. Inhibitors of the Catalytic Subunit 2260 A. Protein Kinase Inhibitor 2260 B. Regulatory Subunits 2262 1. cAMP-Binding Domains 2263 2. Ove...
متن کاملCAMP-dependent Protein Kinase Represses Myogenic Differentiation
Myf-5 and MyoD are members of a family of musclespecific basic helix-loop-helix (bHLH) proteins that are fundamental for myogenic cell differentiation and transcriptional activation of muscle-specific genes. Here we report that elevated levels of the intracellular signaling molecule CAMP and overexpression of CAMP-dependent protein kinase (PKA) inhibit myogenic differentiation. PKA represses...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1989
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)81805-1